Botox is highly toxic—just 1 gram can kill 100 million mice
 Encyclopedic 
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According to reports, botulinum toxin—commonly known as Botox—is a neurotoxin historically used for wrinkle reduction. In recent years, it has gained popularity for injections in limbs and facial areas. When administered locally, it blocks nerve signals to muscles, reducing muscle contraction and achieving slimming effects.
As a muscle relaxant, botulinum toxin can smooth wrinkles and slim the face. As a popular minimally invasive cosmetic procedure, how much do beauty enthusiasts truly understand about its intricacies when choosing this treatment?
The correct method for using botulinum toxin is reportedly as follows:
Typically, 1–2 injection points are selected per side.Injections should be administered as slowly as possible. Post-injection, no local massage or special treatment is required; normal chewing movements will gradually diffuse the solution within the muscle tissue.
Improper use of botulinum toxin can lead to serious complications:
As an intramuscular injection, botulinum toxin has minimal side effects and offers advantages over traditional surgical methods.Local adverse reactions after injecting type A botulinum toxin primarily include excessive weakness of the masseter muscle and corresponding symptoms caused by the toxin's diffusion into adjacent muscle tissue. These clinical manifestations correlate with the injection site and dosage administered. Some patients may experience fever, discomfort, or fatigue following injection. Generally, these symptoms are transient and resolve spontaneously within several weeks.
Botox injection requires precise control of both injection site and dosage. Overdose may cause weakness, balance issues, limping, and in severe cases, life-threatening toxicity. Generally, a safe single injection dose is under 200 units, while 2000 units can be fatal. If accidentally injected into the bloodstream, just 1 gram is lethal to 100 million mice.China has experienced near-fatal cases of botulinum toxin overdose.
Contraindications for botulinum toxin:
1. Patients with myasthenia gravis.
2. Patients with adrenal gland secretion abnormalities.
3. Individuals with heart, liver, kidney, or other organ diseases.
4. Those with allergic constitutions.
5. Pregnant or lactating individuals.
6. Patients with neuromuscular disorders.
7. Individuals who have consumed alcohol (including beer) within the past week.
8. Individuals unable to reduce frequent activity of facial expression muscles.
9. Individuals who have taken aspirin or other antipyretic analgesics within the past two weeks.
10. Individuals using aminoglycoside antibiotics (e.g., gentamicin, streptomycin).
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